Popular Hotels in Seneca 2025

• 

  Lake Keowee Vacation Home

  From $485.00

  4.8 mile from Center

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• 

  Executive Inn of Seneca

  HOTEL

  5.2 mile from Center

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• 

  Hampton Inn & Suites Seneca-Clemson Area

  HOTEL

  From $105.00

  5.2 mile from Center

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• 

  Hampton Inn & Suites Seneca-Clemson Area, SC, Seneca

  HOTEL

  From $104.72

  5.3 mile from Center

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• 

  Best Western Executive Inn - Seneca

  HOTEL

  From $88.00

  5.3 mile from Center

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• 

  Best Way Inn

  5.3 mile from Center

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• 

  Days Inn by Wyndham Seneca

  HOTEL

  From $60.00

  6.3 mile from Center

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• 

  Quality Inn Seneca US-123

  HOTEL

  From $67.00

  6.6 mile from Center

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• 

  Tru By Hilton Seneca Clemson Sc

  HOTEL

  From $91.00

  7.5 mile from Center

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• 

  Tru by Hilton Seneca Clemson, Seneca

  HOTEL

  From $82.80

  7.5 mile from Center

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• 

  Guest Cottage #14 2nd Row & Beyond (P)

  247.1 mile from Center

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