Popular Hotels in Sikeston 2025

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  Holiday Inn Express & Suites Sikeston Southwest

  HOTEL

  From $95.38

  2.2 mile from Center

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• 

  Holiday Inn Express and Suites Sikeston

  From $109.00

  2.2 mile from Center

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• 

  Drury Inn & Suites Sikeston

  From $85.00

  2.3 mile from Center

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• 

  Hampton Inn Sikeston

  From $104.00

  2.4 mile from Center

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• 

  Pear Tree Inn - Sikeston, Sikeston

  HOTEL

  From $76.49

  2.5 mile from Center

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• 

  Comfort Inn & Suites Sikeston I-55

  From $85.00

  2.5 mile from Center

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• 

  Drury Inn & Suites Sikeston, MO, Sikeston

  HOTEL

  From $85.49

  2.5 mile from Center

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• 

  Pear Tree Inn Sikeston

  From $76.00

  2.5 mile from Center

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• 

  Travel Inn and Suites

  From $55.00

  2.5 mile from Center

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• 

  Super 8 by Wyndham Sikeston/Miner Area

  From $54.00

  2.6 mile from Center

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• 

  Days Inn and Suites by Wyndham Sikeston

  From $59.00

  2.7 mile from Center

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• 

  Best Western Plus Sikeston

  From $76.00

  2.9 mile from Center

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• 

  Motel 6 Sikeston Mo

  From $55.00

  2.9 mile from Center

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